PIK3CA mutation in endometriotic epithelial cells promotes viperin-dependent inflammatory response to insulin

Endometrial epithelia are known to harbor cancer driver mutations in the absence of any pathologies, including mutations in PIK3CA. Insulin plays an important role in regulating uterine metabolism during pregnancy, and hyperinsulinemia is associated with conditions impacting fertility. Hyperinsuline...

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Detalles Bibliográficos
Autores principales: Wilson, Mike R., Harkins, Shannon, Reske, Jake J., Siwicki, Rebecca A., Adams, Marie, Bae-Jump, Victoria L., Teixeira, Jose M., Chandler, Ronald L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173629/
https://www.ncbi.nlm.nih.gov/pubmed/37170094
http://dx.doi.org/10.1186/s12958-023-01094-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173629/
https://www.ncbi.nlm.nih.gov/pubmed/37170094
http://dx.doi.org/10.1186/s12958-023-01094-6

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