Dual roles of R-loops in the formation and processing of programmed DNA double-strand breaks during meiosis

BACKGROUND: Meiotic recombination is initiated by Spo11-dependent programmed DNA double-strand breaks (DSBs) that are preferentially concentrated within genomic regions called hotspots; however, the factor(s) that specify the positions of meiotic DSB hotspots remain unclear. RESULTS: Here, we examin...

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Detalles Bibliográficos
Autores principales: Liu, Chao, Xu, Wei, Wang, Liying, Yang, Zhuo, Li, Kuan, Hu, Jun, Chen, Yinghong, Zhang, Ruidan, Xiao, Sai, Liu, Wenwen, Wei, Huafang, Chen, Jia-Yu, Sun, Qianwen, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173651/
https://www.ncbi.nlm.nih.gov/pubmed/37170281
http://dx.doi.org/10.1186/s13578-023-01026-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173651/
https://www.ncbi.nlm.nih.gov/pubmed/37170281
http://dx.doi.org/10.1186/s13578-023-01026-2

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