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HSPB7 oppositely regulates human mesenchymal stromal cell-derived osteogenesis and adipogenesis

BACKGROUND: Recent evidence suggests that accumulation of marrow adipose tissue induced by aberrant lineage allocation of bone marrow-derived mesenchymal stromal cells (BMSCs) contributes to the pathophysiologic processes of osteoporosis. Although master regulators of lineage commitment have been we...

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Detalles Bibliográficos
Autores principales: Zhang, Shuang, van de Peppel, Jeroen, Koedam, Marijke, van Leeuwen, Johannes P. T. M., van der Eerden, Bram C. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173662/
https://www.ncbi.nlm.nih.gov/pubmed/37170285
http://dx.doi.org/10.1186/s13287-023-03361-0