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The size and composition of haplotype reference panels impact the accuracy of imputation from low-pass sequencing in cattle

BACKGROUND: Low-pass sequencing followed by sequence variant genotype imputation is an alternative to the routine microarray-based genotyping in cattle. However, the impact of haplotype reference panels and their interplay with the coverage of low-pass whole-genome sequencing data have not been suff...

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Detalles Bibliográficos
Autores principales: Lloret-Villas, Audald, Pausch, Hubert, Leonard, Alexander S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173671/
https://www.ncbi.nlm.nih.gov/pubmed/37170101
http://dx.doi.org/10.1186/s12711-023-00809-y