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DNMT1 involved in the analgesic effect of folic acid on gastric hypersensitivity through downregulating ASIC1 in adult offspring rats with prenatal maternal stress

AIMS: Gastric hypersensitivity (GHS) is a characteristic pathogenesis of functional dyspepsia (FD). DNA methyltransferase 1 (DNMT1) and acid‐sensing ion channel 1 (ASIC1) are associated with GHS induced by prenatal maternal stress (PMS). The aim of this study was to investigate the mechanism of DNMT...

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Detalles Bibliográficos
Autores principales: Wang, Hong‐Jun, Zhang, Fu‐Chao, Xu, Timothy W., Xu, Yu‐Cheng, Tian, Yuan‐Qing, Wu, Yan‐Yan, Xu, Ji‐Tian, Hu, Shufen, Xu, Guang‐Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173708/
https://www.ncbi.nlm.nih.gov/pubmed/36852448
http://dx.doi.org/10.1111/cns.14131