Downregulation of microRNA‐330‐5p induces manic‐like behaviors in REM sleep‐deprived rats by enhancing tyrosine hydroxylase expression

AIM: In our pilot study, we found an increase in tyrosine hydroxylase (Th) mRNA expression in the prefrontal cortex of 72‐h REM sleep‐deprived (SD) rats, a mania model. Additionally, the expression levels of miR‐325‐3p, miR‐326‐3p, and miR‐330‐5p, the predicted target miRNAs on TH, were significantl...

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Detalles Bibliográficos
Autores principales: Leem, Kang Hyun, Kim, Sanga, Kim, Hee Won, Park, Hae Jeong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2023
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173715/
https://www.ncbi.nlm.nih.gov/pubmed/36794530
http://dx.doi.org/10.1111/cns.14121

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173715/
https://www.ncbi.nlm.nih.gov/pubmed/36794530
http://dx.doi.org/10.1111/cns.14121

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