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Downregulation of microRNA‐330‐5p induces manic‐like behaviors in REM sleep‐deprived rats by enhancing tyrosine hydroxylase expression
AIM: In our pilot study, we found an increase in tyrosine hydroxylase (Th) mRNA expression in the prefrontal cortex of 72‐h REM sleep‐deprived (SD) rats, a mania model. Additionally, the expression levels of miR‐325‐3p, miR‐326‐3p, and miR‐330‐5p, the predicted target miRNAs on TH, were significantl...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173715/ https://www.ncbi.nlm.nih.gov/pubmed/36794530 http://dx.doi.org/10.1111/cns.14121 |