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Actin-rich lamellipodia-like protrusions contribute to the integrity of epithelial cell–cell junctions

Metastasis-suppressor 1 (MTSS1) is a membrane-interacting scaffolding protein that regulates the integrity of epithelial cell–cell junctions and functions as a tumor suppressor in a wide range of carcinomas. MTSS1 binds phosphoinositide-rich membranes through its I-BAR domain and is capable of sensi...

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Detalles Bibliográficos
Autores principales: Senju, Yosuke, Mushtaq, Toiba, Vihinen, Helena, Manninen, Aki, Saarikangas, Juha, Ven, Katharina, Engel, Ulrike, Varjosalo, Markku, Jokitalo, Eija, Lappalainen, Pekka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173786/
https://www.ncbi.nlm.nih.gov/pubmed/36871754
http://dx.doi.org/10.1016/j.jbc.2023.104571