Novel Fab-peptide-HLA-I fusion proteins for redirecting pre-existing anti-CMV T cell immunity to selective eliminate carcinoma cells

Typically, anticancer CD8(pos) T cells occur at low frequencies and become increasingly impaired in the tumor micro environment. In contrast, antiviral CD8(pos) T cells display a much higher polyclonality, frequency, and functionality. In particular, cytomegalovirus (CMV) infection induces high numb...

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Detalles Bibliográficos
Autores principales: Britsch, Isabel, van Wijngaarden, Anne P., Ke, Xiurong, Hendriks, Mark. A.J.M., Samplonius, Douwe F., Ploeg, Emily M., Helfrich, Wijnand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2023
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173793/
https://www.ncbi.nlm.nih.gov/pubmed/37180637
http://dx.doi.org/10.1080/2162402X.2023.2207868

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173793/
https://www.ncbi.nlm.nih.gov/pubmed/37180637
http://dx.doi.org/10.1080/2162402X.2023.2207868

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