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Novel Fab-peptide-HLA-I fusion proteins for redirecting pre-existing anti-CMV T cell immunity to selective eliminate carcinoma cells
Typically, anticancer CD8(pos) T cells occur at low frequencies and become increasingly impaired in the tumor micro environment. In contrast, antiviral CD8(pos) T cells display a much higher polyclonality, frequency, and functionality. In particular, cytomegalovirus (CMV) infection induces high numb...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Taylor & Francis
2023
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173793/ https://www.ncbi.nlm.nih.gov/pubmed/37180637 http://dx.doi.org/10.1080/2162402X.2023.2207868 |