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Bone marrow mesenchymal stem cell-derived exosomal microRNAs target PI3K/Akt signaling pathway to promote the activation of fibroblasts

BACKGROUND: Fibroblast plays a major role in tendon-bone healing. Exosomes derived from bone marrow mesenchymal stem cells (BMSCs) can activate fibroblasts and promote tendon-bone healing via the contained microRNAs (miRNAs). However, the underlying mechanism is not comprehensively understood. Herei...

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Detalles Bibliográficos
Autores principales: Li, Fang-Qi, Chen, Wen-Bo, Luo, Zhi-Wen, Chen, Yi-Sheng, Sun, Ya-Ying, Su, Xiao-Ping, Sun, Jun-Ming, Chen, Shi-Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173806/
https://www.ncbi.nlm.nih.gov/pubmed/37181002
http://dx.doi.org/10.4252/wjsc.v15.i4.248