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Targeting Sigma Receptors for the Treatment of Neurodegenerative and Neurodevelopmental Disorders
The sigma-1 receptor is a 223 amino acid-long protein with a recently identified structure. The sigma-2 receptor is a genetically unrelated protein with a similarly shaped binding pocket and acts to influence cellular activities similar to the sigma-1 receptor. Both proteins are highly expressed in...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10173947/ https://www.ncbi.nlm.nih.gov/pubmed/37166702 http://dx.doi.org/10.1007/s40263-023-01007-6 |