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TLR7 modulates extramedullary splenic erythropoiesis in P. yoelii NSM-infected mice through the regulation of iron metabolism of macrophages with IFN-γ

Splenomegaly is a prominent clinical manifestation of malaria and the causes remain incompletely clear. Anemia is induced in malaria and extramedullary splenic erythropoiesis is compensation for the loss of erythrocytes. However, the regulation of extramedullary splenic erythropoiesis in malaria is...

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Detalles Bibliográficos
Autores principales: Li, Jiajie, Liu, Lin, Xing, Junmin, Chen, Dianhui, Fang, Chao, Mo, Feng, Gong, Yumei, Tan, Zhengrong, Liang, Guikuan, Xiao, Wei, Tang, Shanni, Wei, Haixia, Zhao, Shan, Xie, Hongyan, Pan, Xingfei, Yin, Xiaomao, Huang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174296/
https://www.ncbi.nlm.nih.gov/pubmed/37180169
http://dx.doi.org/10.3389/fimmu.2023.1123074