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Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus
Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine inflammatory response at insemination, but its precise mechanism at molecular-level remains unknown. According to the ligand specificity, TLR2 forms a heterodimer with TLR1 or TLR6 as an initial step to mediate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174305/ https://www.ncbi.nlm.nih.gov/pubmed/37180107 http://dx.doi.org/10.3389/fimmu.2023.1158090 |