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Sperm activate TLR2/TLR1 heterodimerization to induce a weak proinflammatory response in the bovine uterus

Toll-like receptor 2 (TLR2) signaling pathway is involved in the sperm-triggered uterine inflammatory response at insemination, but its precise mechanism at molecular-level remains unknown. According to the ligand specificity, TLR2 forms a heterodimer with TLR1 or TLR6 as an initial step to mediate...

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Detalles Bibliográficos
Autores principales: Mansouri, Alireza, Yousef, Mohamed Samy, Kowsar, Rasoul, Usui, Nonoka, Akthar, Ihshan, Miyamoto, Akio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174305/
https://www.ncbi.nlm.nih.gov/pubmed/37180107
http://dx.doi.org/10.3389/fimmu.2023.1158090

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