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Oxygen therapeutic window induced by myo-inositol trispyrophosphate (ITPP)–Local pO(2) study in murine tumors

Hypoxia, an inevitable feature of locally advanced solid tumors, has been known as an adverse prognostic factor, a driver of an aggressive phenotype, and an unfavorable factor in therapies. Myo-inositol trispyrophosphate (ITPP) is a hemoglobin modifier known to both increase O(2) release and normali...

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Detalles Bibliográficos
Autores principales: Krzykawska-Serda, Martyna, Szczygieł, Dariusz, Gaweł, Szymon, Drzał, Agnieszka, Szczygieł, Małgorzata, Kmieć, Maciej M., Mackiewicz, Andrzej, Kieda, Claudine, Elas, Martyna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174508/
https://www.ncbi.nlm.nih.gov/pubmed/37167239
http://dx.doi.org/10.1371/journal.pone.0285318