Cargando…
Oxygen therapeutic window induced by myo-inositol trispyrophosphate (ITPP)–Local pO(2) study in murine tumors
Hypoxia, an inevitable feature of locally advanced solid tumors, has been known as an adverse prognostic factor, a driver of an aggressive phenotype, and an unfavorable factor in therapies. Myo-inositol trispyrophosphate (ITPP) is a hemoglobin modifier known to both increase O(2) release and normali...
Autores principales: | Krzykawska-Serda, Martyna, Szczygieł, Dariusz, Gaweł, Szymon, Drzał, Agnieszka, Szczygieł, Małgorzata, Kmieć, Maciej M., Mackiewicz, Andrzej, Kieda, Claudine, Elas, Martyna |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174508/ https://www.ncbi.nlm.nih.gov/pubmed/37167239 http://dx.doi.org/10.1371/journal.pone.0285318 |
Ejemplares similares
-
Treatment of hypoxia‐dependent cardiovascular diseases by myo‐inositol trispyrophosphate (ITPP)‐enhancement of oxygen delivery by red blood cells
por: Oknińska, Marta, et al.
Publicado: (2020) -
Impact of myo‐inositol trispyrophosphate (ITPP) on tumour oxygenation and response to irradiation in rodent tumour models
por: Tran, Ly‐Binh‐An, et al.
Publicado: (2018) -
Right ventricular myocardial oxygen tension is reduced in monocrotaline-induced pulmonary hypertension in the rat and restored by myo-inositol trispyrophosphate
por: Oknińska, Marta, et al.
Publicado: (2021) -
Tumour angiogenesis normalized by myo‐inositol trispyrophosphate alleviates hypoxia in the microenvironment and promotes antitumor immune response
por: El Hafny‐Rahbi, Bouchra, et al.
Publicado: (2021) -
Stable tumor vessel normalization with pO(2) increase and endothelial PTEN activation by inositol trispyrophosphate brings novel tumor treatment
por: Kieda, Claudine, et al.
Publicado: (2013)