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Identification of diphenylurea derivatives as novel endocytosis inhibitors that demonstrate broad-spectrum activity against SARS-CoV-2 and influenza A virus both in vitro and in vivo

Rapid evolution of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and influenza A virus (IAV) poses enormous challenge in the development of broad-spectrum antivirals that are effective against the existing and emerging viral strains. Virus entry through endocytosis represents an attra...

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Detalles Bibliográficos
Autores principales: Kumar, Nirmal, Taily, Irshad Maajid, Singh, Charandeep, Kumar, Sahil, Rajmani, Raju S., Chakraborty, Debajyoti, Sharma, Anshul, Singh, Priyanka, Thakur, Krishan Gopal, Varadarajan, Raghavan, Ringe, Rajesh P., Banerjee, Prabal, Banerjee, Indranil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174524/
https://www.ncbi.nlm.nih.gov/pubmed/37126530
http://dx.doi.org/10.1371/journal.ppat.1011358