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Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3D(pol) to membranes

Picornavirus genome replication takes place in specialized intracellular membrane compartments that concentrate viral RNA and proteins as well as a number of host factors that also participate in the process. The core enzyme in the replication machinery is the viral RNA-dependent RNA polymerase (RdR...

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Detalles Bibliográficos
Autores principales: Ferrer-Orta, Cristina, Ferrero, Diego S., Verdaguer, Nuria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174528/
https://www.ncbi.nlm.nih.gov/pubmed/37126532
http://dx.doi.org/10.1371/journal.ppat.1011373