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Dual role of the foot-and-mouth disease virus 3B1 protein in the replication complex: As protein primer and as an essential component to recruit 3D(pol) to membranes
Picornavirus genome replication takes place in specialized intracellular membrane compartments that concentrate viral RNA and proteins as well as a number of host factors that also participate in the process. The core enzyme in the replication machinery is the viral RNA-dependent RNA polymerase (RdR...
Autores principales: | Ferrer-Orta, Cristina, Ferrero, Diego S., Verdaguer, Nuria |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174528/ https://www.ncbi.nlm.nih.gov/pubmed/37126532 http://dx.doi.org/10.1371/journal.ppat.1011373 |
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