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A conserved Y-shaped RNA structure in the 3’UTR of chikungunya virus genome as a host-specialized element that modulates viral replication and evolution

RNA viral genomes compact information into functional RNA structures. Here, using chikungunya virus as a model, we investigated the structural requirements of conserved RNA elements in the 3’ untranslated region (3’UTR) for viral replication in mosquito and mammalian cells. Using structural predicti...

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Detalles Bibliográficos
Autores principales: Bardossy, Eugenia Soledad, Volpe, Sebastiano, Alvarez, Diego Ezequiel, Filomatori, Claudia Verónica
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174580/
https://www.ncbi.nlm.nih.gov/pubmed/37126493
http://dx.doi.org/10.1371/journal.ppat.1011352