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AcrNET: predicting anti-CRISPR with deep learning

MOTIVATION: As an important group of proteins discovered in phages, anti-CRISPR inhibits the activity of the immune system of bacteria (i.e. CRISPR-Cas), offering promise for gene editing and phage therapy. However, the prediction and discovery of anti-CRISPR are challenging due to their high variab...

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Detalles Bibliográficos
Autores principales: Li, Yunxiang, Wei, Yumeng, Xu, Sheng, Tan, Qingxiong, Zong, Licheng, Wang, Jiuming, Wang, Yixuan, Chen, Jiayang, Hong, Liang, Li, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174705/
https://www.ncbi.nlm.nih.gov/pubmed/37084259
http://dx.doi.org/10.1093/bioinformatics/btad259