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Mapping the motion and structure of flexible proteins from cryo-EM data

A deep learning algorithm maps out the continuous conformational changes of flexible protein molecules from single-particle cryo-electron microscopy images, allowing the visualization of the conformational landscape of a protein with improved resolution of its moving parts.

Detalles Bibliográficos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174731/
https://www.ncbi.nlm.nih.gov/pubmed/37169930
http://dx.doi.org/10.1038/s41592-023-01883-2