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Correlation of gene expression profiles to identify pancreatic cancer cell lines that best model primary human tumors

BACKGROUND: Cancer cell lines are important research models for studying tumor biology in vivo. The accuracy of such studies is highly dependent on the phenotypic and genetic similarity of cell lines to patient tumors, but this is not always the case, particularly for pancreatic cancer. METHODS: We...

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Detalles Bibliográficos
Autores principales: Hu, Yan, Gao, Peng, Xu, Gaoqi, Sun, Jiao, Xin, Wenxiu, Kong, Sisi, Ding, Haiying, Zhu, Junfeng, Fang, Luo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10174970/
https://www.ncbi.nlm.nih.gov/pubmed/37180676
http://dx.doi.org/10.21037/tcr-23-173