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One- and Two-Dose Vaccinations With Modified Vaccinia Ankara-Bavarian Nordic Induce Durable B-Cell Memory Responses Comparable to Replicating Smallpox Vaccines

BACKGROUND: Although modified vaccinia Ankara-Bavarian Nordic (MVA-BN) vaccination is approved for smallpox and monkeypox prevention, immunological persistence and booster effects remain undescribed. METHODS: Participants naive to smallpox vaccination were randomized to 1 dose MVA-BN (1×MVA, n = 181...

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Detalles Bibliográficos
Autores principales: Ilchmann, Heiko, Samy, Nathaly, Reichhardt, Daniela, Schmidt, Darja, Powell, Jacqueline D, Meyer, Thomas P H, Silbernagl, Günter, Nichols, Rick, Weidenthaler, Heinz, De Moerlooze, Laurence, Chen, Liddy, Chaplin, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175071/
https://www.ncbi.nlm.nih.gov/pubmed/36408618
http://dx.doi.org/10.1093/infdis/jiac455