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Genetically prolonged beige fat in male mice confers long-lasting metabolic health

A potential therapeutic target to curb obesity and diabetes is thermogenic beige adipocytes. However, beige adipocytes quickly transition into white adipocytes upon removing stimuli. Here, we define the critical role of cyclin dependent kinase inhibitor 2A (Cdkn2a) as a molecular pedal for the beige...

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Detalles Bibliográficos
Autores principales: Wu, Ruifan, Park, Jooman, Qian, Yanyu, Shi, Zuoxiao, Hu, Ruoci, Yuan, Yexian, Xiong, Shaolei, Wang, Zilai, Yan, Gege, Ong, Sang-Ging, Song, Qing, Song, Zhenyuan, Mahmoud, Abeer M., Xu, Pingwen, He, Congcong, Arpke, Robert W., Kyba, Michael, Shu, Gang, Jiang, Qingyan, Jiang, Yuwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175245/
https://www.ncbi.nlm.nih.gov/pubmed/37169793
http://dx.doi.org/10.1038/s41467-023-38471-z