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Maternal separation leads to dynamic changes of visceral hypersensitivity and fecal metabolomics from childhood to adulthood

We assessed dynamic changes in visceral hypersensitivity and fecal metabolomics through a mouse model of irritable bowel syndrome (IBS) from childhood to adulthood. A mouse model of IBS was constructed with maternal separation (MS) in early life. Male mice aged 25, 40, and 70 days were used. Viscera...

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Detalles Bibliográficos
Autores principales: Chen, Xiaolong, Hu, Chenmin, Yan, Chenxi, Tao, Enfu, Zhu, Zhenya, Shu, Xiaoli, Guo, Rui, Jiang, Mizu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175246/
https://www.ncbi.nlm.nih.gov/pubmed/37169847
http://dx.doi.org/10.1038/s41598-023-34792-7