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Comparison of the effects of oxidative and inflammatory stresses on rat chondrocyte senescence

Osteoarthritis (OA) is an age-related degenerative joint disease that causes progressive cartilage loss. Chondrocyte senescence is a fundamental mechanism that contributes to the imbalance of matrix homeostasis in OA by inducing senescence-associated secretory phenotype (SASP). Although OA chondrocy...

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Detalles Bibliográficos
Autores principales: Yagi, Misaki, Endo, Kentaro, Komori, Keiichiro, Sekiya, Ichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175275/
https://www.ncbi.nlm.nih.gov/pubmed/37169906
http://dx.doi.org/10.1038/s41598-023-34825-1