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Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2

In actively translating 80S ribosomes the ribosomal protein eS7 of the 40S subunit is monoubiquitinated by the E3 ligase Not4 and deubiquitinated by Otu2 upon ribosomal subunit recycling. Despite its importance for translation efficiency the exact role and structural basis for this translational res...

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Detalles Bibliográficos
Autores principales: Ikeuchi, Ken, Ivic, Nives, Buschauer, Robert, Cheng, Jingdong, Fröhlich, Thomas, Matsuo, Yoshitaka, Berninghausen, Otto, Inada, Toshifumi, Becker, Thomas, Beckmann, Roland
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175282/
https://www.ncbi.nlm.nih.gov/pubmed/37169754
http://dx.doi.org/10.1038/s41467-023-38161-w