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p140Cap inhibits β-Catenin in the breast cancer stem cell compartment instructing a protective anti-tumor immune response

The p140Cap adaptor protein is a tumor suppressor in breast cancer associated with a favorable prognosis. Here we highlight a function of p140Cap in orchestrating local and systemic tumor-extrinsic events that eventually result in inhibition of the polymorphonuclear myeloid-derived suppressor cell f...

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Detalles Bibliográficos
Autores principales: Salemme, Vincenzo, Vedelago, Mauro, Sarcinella, Alessandro, Moietta, Federico, Piccolantonio, Alessio, Moiso, Enrico, Centonze, Giorgia, Manco, Marta, Guala, Andrea, Lamolinara, Alessia, Angelini, Costanza, Morellato, Alessandro, Natalini, Dora, Calogero, Raffaele, Incarnato, Danny, Oliviero, Salvatore, Conti, Laura, Iezzi, Manuela, Tosoni, Daniela, Bertalot, Giovanni, Freddi, Stefano, Tucci, Francesco A., De Sanctis, Francesco, Frusteri, Cristina, Ugel, Stefano, Bronte, Vincenzo, Cavallo, Federica, Provero, Paolo, Gai, Marta, Taverna, Daniela, Turco, Emilia, Pece, Salvatore, Defilippi, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175288/
https://www.ncbi.nlm.nih.gov/pubmed/37169737
http://dx.doi.org/10.1038/s41467-023-37824-y