Base-resolution UV footprinting by sequencing reveals distinctive damage signatures for DNA-binding proteins

Decades ago, it was shown that proteins binding to DNA can quantitatively alter the formation of DNA damage by UV light. This established the principle of UV footprinting for non-intrusive study of protein-DNA contacts in living cells, albeit at limited scale and precision. Here, we perform deep bas...

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Detalles Bibliográficos
Autores principales: Elliott, Kerryn, Singh, Vinod Kumar, Boström, Martin, Larsson, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175305/
https://www.ncbi.nlm.nih.gov/pubmed/37169761
http://dx.doi.org/10.1038/s41467-023-38266-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175305/
https://www.ncbi.nlm.nih.gov/pubmed/37169761
http://dx.doi.org/10.1038/s41467-023-38266-2

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