The association between age at breast cancer diagnosis and prevalence of pathogenic variants

PURPOSE: Young age at breast cancer (BC) diagnosis and family history of BC are strongly associated with high prevalence of pathogenic variants (PVs) in BRCA1 and BRCA2 genes. There is limited evidence for such associations with moderate/high penetrance BC-risk genes such as ATM, CHEK2, and PALB2. M...

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Detalles Bibliográficos
Autores principales: Daly, Mary B., Rosenthal, Eric, Cummings, Shelly, Bernhisel, Ryan, Kidd, John, Hughes, Elisha, Gutin, Alexander, Meek, Stephanie, Slavin, Thomas P., Kurian, Allison W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Original Laboratory Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175307/
https://www.ncbi.nlm.nih.gov/pubmed/37084156
http://dx.doi.org/10.1007/s10549-023-06946-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175307/
https://www.ncbi.nlm.nih.gov/pubmed/37084156
http://dx.doi.org/10.1007/s10549-023-06946-8

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