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Population Pharmacokinetic and Pharmacodynamic Modeling of Fesoterodine in Pediatric Patients with Neurogenic Detrusor Overactivity

BACKGROUND AND OBJECTIVE: Fesoterodine is a muscarinic receptor antagonist approved for the treatment of overactive bladder (OAB) in adults and neurogenic detrusor overactivity (NDO) in pediatric patients. This work aimed to characterize the population pharmacokinetics of 5-hydroxymethyl tolterodine...

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Detalles Bibliográficos
Autores principales: Sano, Yamato, Shoji, Satoshi, Shahin, Mohamed, Sweeney, Kevin, Darekar, Amanda, Malhotra, Bimal K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175358/
https://www.ncbi.nlm.nih.gov/pubmed/36892754
http://dx.doi.org/10.1007/s13318-023-00818-8