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Association of baseline ROR1 and ROR2 gene expression with clinical outcomes in the I-SPY2 neoadjuvant breast cancer trial

PURPOSE: ROR1 and ROR2 are Type 1 tyrosine kinase-like orphan receptors for Wnt5a that are associated with breast cancer progression. Experimental agents targeting ROR1 and ROR2 are in clinical trials. This study evaluated whether expression levels of ROR1 or ROR2 correlated with one another or with...

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Detalles Bibliográficos
Autores principales: Parker, Barbara A., Shatsky, Rebecca A., Schwab, Richard B., Wallace, Anne M., Wolf, Denise M., Hirst, Gillian L., Brown-Swigart, Lamorna, Esserman, Laura J., van ’t Veer, Laura J., Ghia, Emanuela M., Yau, Christina, Kipps, Thomas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175386/
https://www.ncbi.nlm.nih.gov/pubmed/37029329
http://dx.doi.org/10.1007/s10549-023-06914-2