Cargando…

Detecting recurrent passenger mutations in melanoma by targeted UV damage sequencing

Sequencing of melanomas has identified hundreds of recurrent mutations in both coding and non-coding DNA. These include a number of well-characterized oncogenic driver mutations, such as coding mutations in the BRAF and NRAS oncogenes, and non-coding mutations in the promoter of telomerase reverse t...

Descripción completa

Detalles Bibliográficos
Autores principales: Selvam, Kathiresan, Sivapragasam, Smitha, Poon, Gregory M. K., Wyrick, John J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175485/
https://www.ncbi.nlm.nih.gov/pubmed/37169747
http://dx.doi.org/10.1038/s41467-023-38265-3