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Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment

While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing evidence that an early life immune activation can contribute to the disease pathogenesis. When we mimicked an early systemic viral infection or applied murine...

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Detalles Bibliográficos
Autores principales: Schwabenland, Marius, Mossad, Omar, Sievert, Annika, Peres, Adam G., Ringel, Elena, Baasch, Sebastian, Kolter, Julia, Cascone, Giulia, Dokalis, Nikolaos, Vlachos, Andreas, Ruzsics, Zsolt, Henneke, Philipp, Prinz, Marco, Blank, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175500/
https://www.ncbi.nlm.nih.gov/pubmed/37169749
http://dx.doi.org/10.1038/s41467-023-38373-0