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Neonatal immune challenge poses a sex-specific risk for epigenetic microglial reprogramming and behavioral impairment
While the precise processes underlying a sex bias in the development of central nervous system (CNS) disorders are unknown, there is growing evidence that an early life immune activation can contribute to the disease pathogenesis. When we mimicked an early systemic viral infection or applied murine...
Autores principales: | Schwabenland, Marius, Mossad, Omar, Sievert, Annika, Peres, Adam G., Ringel, Elena, Baasch, Sebastian, Kolter, Julia, Cascone, Giulia, Dokalis, Nikolaos, Vlachos, Andreas, Ruzsics, Zsolt, Henneke, Philipp, Prinz, Marco, Blank, Thomas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175500/ https://www.ncbi.nlm.nih.gov/pubmed/37169749 http://dx.doi.org/10.1038/s41467-023-38373-0 |
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