H(2)O(2) selectively damages the binuclear iron-sulfur cluster N1b of respiratory complex I

NADH:ubiquinone oxidoreductase, respiratory complex I, plays a major role in cellular energy metabolism by coupling electron transfer with proton translocation. Electron transfer is catalyzed by a flavin mononucleotide and a series of iron-sulfur (Fe/S) clusters. As a by-product of the reaction, the...

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Detalles Bibliográficos
Autores principales: Strotmann, Lisa, Harter, Caroline, Gerasimova, Tatjana, Ritter, Kevin, Jessen, Henning J., Wohlwend, Daniel, Friedrich, Thorsten
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175503/
https://www.ncbi.nlm.nih.gov/pubmed/37169846
http://dx.doi.org/10.1038/s41598-023-34821-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175503/
https://www.ncbi.nlm.nih.gov/pubmed/37169846
http://dx.doi.org/10.1038/s41598-023-34821-5

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