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H(2)O(2) selectively damages the binuclear iron-sulfur cluster N1b of respiratory complex I
NADH:ubiquinone oxidoreductase, respiratory complex I, plays a major role in cellular energy metabolism by coupling electron transfer with proton translocation. Electron transfer is catalyzed by a flavin mononucleotide and a series of iron-sulfur (Fe/S) clusters. As a by-product of the reaction, the...
Autores principales: | Strotmann, Lisa, Harter, Caroline, Gerasimova, Tatjana, Ritter, Kevin, Jessen, Henning J., Wohlwend, Daniel, Friedrich, Thorsten |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175503/ https://www.ncbi.nlm.nih.gov/pubmed/37169846 http://dx.doi.org/10.1038/s41598-023-34821-5 |
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