PALB2 germline mutations in a large cohort of Middle Eastern breast-ovarian cancer patients

The PALB2 gene is a breast cancer (BC) and ovarian cancer (OC) predisposition gene involved in the homologous recombination repair pathway. However, the prevalence and clinicopathological association of PALB2 pathogenic/likely pathogenic (PV/LPV) variants in Middle East is still not fully explored....

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Detalles Bibliográficos
Autores principales: Siraj, Abdul K., Bu, Rong, Parvathareddy, Sandeep Kumar, Iqbal, Kaleem, Azam, Saud, Qadri, Zeeshan, Al-Rasheed, Maha, Haqawi, Wael, Diaz, Mark, Victoria, Ingrid G., Al-Badawi, Ismail A., Tulbah, Asma, Al-Dayel, Fouad, Ajarim, Dahish, Al-Kuraya, Khawla S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2023
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175539/
https://www.ncbi.nlm.nih.gov/pubmed/37169825
http://dx.doi.org/10.1038/s41598-023-34693-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175539/
https://www.ncbi.nlm.nih.gov/pubmed/37169825
http://dx.doi.org/10.1038/s41598-023-34693-9

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