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Two single-point mutations in Ankyrin Repeat one drastically change the threshold temperature of TRPV1
TRPV1 plays an important role in the thermosensory system; however, the mechanism controlling its heat activation property is not well understood. Here, we determine the heat activation properties of TRPV1 cloned from tailed amphibians, which prefer cooler environments, finding the threshold tempera...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2023
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175561/ https://www.ncbi.nlm.nih.gov/pubmed/37169739 http://dx.doi.org/10.1038/s41467-023-38051-1 |