Immune desert in MMR-deficient tumors predicts poor responsiveness of immune checkpoint inhibition

BACKGROUND: Although many efforts have been devoted to identify biomarkers to predict the responsiveness of immune checkpoint inhibitors, including expression of programmed death-ligand 1 (PD-L1) and major histocompatibility complex (MHC) I, microsatellite instability (MSI), mismatch repair (MMR) de...

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Detalles Bibliográficos
Autores principales: Zheng, Guoxing, Lu, Yingsi, Yang, Zheng, Chen, Hong, Liang, Qian, Zhu, Qingqing, Li, Yan, Xiao, Xing, He, Zhuzhen, Zhu, Yifan, Li, Bo, Huang, Leilei, Dong, Nan, Hu, Shuang, Pan, Yihang, Zhang, Changhua, Zhu, Chengming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175608/
https://www.ncbi.nlm.nih.gov/pubmed/37187745
http://dx.doi.org/10.3389/fimmu.2023.1142862

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175608/
https://www.ncbi.nlm.nih.gov/pubmed/37187745
http://dx.doi.org/10.3389/fimmu.2023.1142862

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