Inhibition of growth and contraction in human prostate stromal cells by silencing of NUAK1 and -2, and by the presumed NUAK inhibitors HTH01-015 and WZ4003

Background: NUAKs promote myosin light chain phosphorlyation, actin organization, proliferation and suppression of cell death in non-muscle cells, which are critical for smooth muscle contraction and growth. In benign prostatic hyperplasia (BPH), contraction and growth in the prostate drive urethral...

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Detalles Bibliográficos
Autores principales: Liu, Yuhan, Wang, Ruixiao, Huang, Ru, Rutz, Beata, Ciotkowska, Anna, Tamalunas, Alexander, Hu, Sheng, Trieb, Moritz, Waidelich, Raphaela, Strittmatter, Frank, Stief, Christian G., Hennenberg, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175612/
https://www.ncbi.nlm.nih.gov/pubmed/37188272
http://dx.doi.org/10.3389/fphar.2023.1105427

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175612/
https://www.ncbi.nlm.nih.gov/pubmed/37188272
http://dx.doi.org/10.3389/fphar.2023.1105427

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