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Histone lactylation driven by mROS-mediated glycolytic shift promotes hypoxic pulmonary hypertension
Increased mitochondrial reactive oxygen species (mROS) and glycolysis have been established in pulmonary hypertension (PH). However, the effect of elevated mROS on glycolytic shift and how increased glycolysis promotes hypoxic pulmonary artery smooth muscle cell (PASMC) proliferation and vascular re...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175659/ https://www.ncbi.nlm.nih.gov/pubmed/36564027 http://dx.doi.org/10.1093/jmcb/mjac073 |