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Histone lactylation driven by mROS-mediated glycolytic shift promotes hypoxic pulmonary hypertension

Increased mitochondrial reactive oxygen species (mROS) and glycolysis have been established in pulmonary hypertension (PH). However, the effect of elevated mROS on glycolytic shift and how increased glycolysis promotes hypoxic pulmonary artery smooth muscle cell (PASMC) proliferation and vascular re...

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Detalles Bibliográficos
Autores principales:	Chen, Jian, Zhang, Meiling, Liu, Yanjie, Zhao, Shihong, Wang, Yanxia, Wang, Meng, Niu, Wen, Jin, Faguang, Li, Zhichao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175659/ https://www.ncbi.nlm.nih.gov/pubmed/36564027 http://dx.doi.org/10.1093/jmcb/mjac073

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