Stress resilience-enhancing drugs preserve tissue structure and function in degenerating retina via phosphodiesterase inhibition

Chronic, progressive retinal diseases, such as age-related macular degeneration (AMD), diabetic retinopathy, and retinitis pigmentosa, arise from genetic and environmental perturbations of cellular and tissue homeostasis. These disruptions accumulate with repeated exposures to stress over time, lead...

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Detalles Bibliográficos
Autores principales: C. Luu, Jennings, Saadane, Aicha, Leinonen, Henri, H. Choi, Elliot, Gao, Fangyuan, Lewandowski, Dominik, Halabi, Maximilian, L. Sander, Christopher, Wu, Arum, Wang, Jacob M., Singh, Rupesh, Gao, Songqi, Lessieur, Emma M., Dong, Zhiqian, Palczewska, Grazyna, Mullins, Robert F., Peachey, Neal S., Kiser, Philip D., Tabaka, Marcin, Kern, Timothy S., Palczewski, Krzysztof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175720/
https://www.ncbi.nlm.nih.gov/pubmed/37126699
http://dx.doi.org/10.1073/pnas.2221045120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175720/
https://www.ncbi.nlm.nih.gov/pubmed/37126699
http://dx.doi.org/10.1073/pnas.2221045120

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