High sensitivity top–down proteomics captures single muscle cell heterogeneity in large proteoforms

Single-cell proteomics has emerged as a powerful method to characterize cellular phenotypic heterogeneity and the cell-specific functional networks underlying biological processes. However, significant challenges remain in single-cell proteomics for the analysis of proteoforms arising from genetic m...

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Detalles Bibliográficos
Autores principales: Melby, Jake A., Brown, Kyle A., Gregorich, Zachery R., Roberts, David S., Chapman, Emily A., Ehlers, Lauren E., Gao, Zhan, Larson, Eli J., Jin, Yutong, Lopez, Justin R., Hartung, Jared, Zhu, Yanlong, McIlwain, Sean J., Wang, Daojing, Guo, Wei, Diffee, Gary M., Ge, Ying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175728/
https://www.ncbi.nlm.nih.gov/pubmed/37126723
http://dx.doi.org/10.1073/pnas.2222081120

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175728/
https://www.ncbi.nlm.nih.gov/pubmed/37126723
http://dx.doi.org/10.1073/pnas.2222081120

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