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Nanoelectrochemistry reveals how soluble Aβ(42) oligomers alter vesicular storage and release of glutamate

Glutamate (Glu) is the major excitatory transmitter in the nervous system. Impairment of its vesicular release by β-amyloid (Aβ) oligomers is thought to participate in pathological processes leading to Alzheimer’s disease. However, it remains unclear whether soluble Aβ(42) oligomers affect intravesi...

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Detalles Bibliográficos
Autores principales: Yang, Xiao-Ke, Zhang, Fu-Li, Jin, Xue-Ke, Jiao, Yu-Ting, Zhang, Xin-Wei, Liu, Yan-Ling, Amatore, Christian, Huang, Wei-Hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175745/
https://www.ncbi.nlm.nih.gov/pubmed/37126689
http://dx.doi.org/10.1073/pnas.2219994120