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Interplay among differential exposure to Mycobacterium leprae and TLR4 polymorphism impacts the immune response in household contacts of leprosy patients

INTRODUCTION: The aim of the present study was to investigate the association between the single nucleotide polymorphism (SNP) rs1927914 A/G in TLR4 gene and the immunological profile of household contacts (HHC) of leprosy patients. Leprosy classification is usually complex and requires the assessme...

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Detalles Bibliográficos
Autores principales: Cunha, Eloisa Helena Medeiros, Marçal, Pedro Henrique Ferreira, Gama, Rafael Silva, de Oliveira, Lorena Bruna Pereira, Pinheiro, Roberta Olmo, Sarno, Euzenir Nunes, Brito-de-Sousa, Joaquim Pedro, de Souza, Márcio Luís Moreira, Fairley, Jessica Kathleen, Valente, Thaisa Netto Souza, Velloso-Rodrigues, Cibele, Martins-Filho, Olindo Assis, de Oliveira, Dirce Ribeiro, Fraga, Lucia Alves de Oliveira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2023
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175789/
https://www.ncbi.nlm.nih.gov/pubmed/37187734
http://dx.doi.org/10.3389/fimmu.2023.1130137