Cargando…
Interplay among differential exposure to Mycobacterium leprae and TLR4 polymorphism impacts the immune response in household contacts of leprosy patients
INTRODUCTION: The aim of the present study was to investigate the association between the single nucleotide polymorphism (SNP) rs1927914 A/G in TLR4 gene and the immunological profile of household contacts (HHC) of leprosy patients. Leprosy classification is usually complex and requires the assessme...
Autores principales: | Cunha, Eloisa Helena Medeiros, Marçal, Pedro Henrique Ferreira, Gama, Rafael Silva, de Oliveira, Lorena Bruna Pereira, Pinheiro, Roberta Olmo, Sarno, Euzenir Nunes, Brito-de-Sousa, Joaquim Pedro, de Souza, Márcio Luís Moreira, Fairley, Jessica Kathleen, Valente, Thaisa Netto Souza, Velloso-Rodrigues, Cibele, Martins-Filho, Olindo Assis, de Oliveira, Dirce Ribeiro, Fraga, Lucia Alves de Oliveira |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2023
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10175789/ https://www.ncbi.nlm.nih.gov/pubmed/37187734 http://dx.doi.org/10.3389/fimmu.2023.1130137 |
Ejemplares similares
-
Algorithm Design for a Cytokine Release Assay of Antigen-Specific In Vitro Stimuli of Circulating Leukocytes to Classify Leprosy Patients and Household Contacts
por: Marçal, Pedro Henrique Ferreira, et al.
Publicado: (2022) -
Functional biomarker signatures of circulating T-cells and its association with distinct clinical status of leprosy patients and their respective household contacts
por: Marçal, Pedro Henrique Ferreira, et al.
Publicado: (2020) -
Gene Expression Profile of Mycobacterium leprae Contribution in the Pathology of Leprosy Neuropathy
por: de Souza, Beatriz Junqueira, et al.
Publicado: (2022) -
High frequency of M. leprae DNA detection in asymptomatic household contacts
por: Gama, Rafael Silva, et al.
Publicado: (2018) -
Serum IgA Antibodies Specific to M. leprae Antigens as Biomarkers for Leprosy Detection and Household Contact Tracking
por: Silva, Kyssia Karen de Paiva e, et al.
Publicado: (2021)